DNA Essays -- Biology Biological Essays

DNA "There is no substance as important as DNA," Watson, 1991. Gene therapy is a controversial issue in today’s science society. Debates in the United States are covering a wide range of topics. I will discuss just a few viewpoints from both sides. First of all, a little background on DNA and genetics. DNA, or deoxyribonucleic acid, is a complex structure consisting of a double stranded helix made up of complementary base pairs. Adenine (A) pairs up with thymine (T) and guanine (G) matches with cytosine (C). They are held together with the help of hydrogen bonds. The helix is spiral shaped, and the outside of DNA is alternating sugar and phosphate groups. Watson and Crick presented this structure in 1953. "The genetic code is imprinted in the precise sequence of the nitrogenous bases running down the length of DNA molecule." Lee, 1993. A base triplet code is made up of three nucleotides. Each DNA triplet code is translated via a messenger RNA into a protein. DNA has a semiconservative replication process where the double strands unwind and serve as templates. A genome is a collection of DNA molecules that make up am organism. There is great diversity between different species and even between the same species. "The human genome contains up to three billion base pairs, the genetic difference among individual humans is as much as three million base pairs of DNA" (Davis, 1990). A mutation is where a gene is changed to another form. A mutation does not imply a bad thing happened. They can be deleterious, cause disease, reduce fitness or even be lethal. A mutation can also be beneficial if it increases adaptability or advantages in a species. Or a mutation can be silent and cause no apparent change in the organism. T... ...ecoming a safer, more efficient process that may some day cure the world of all genetic disease. Some day, being sick may just mean getting gene therapy. Bibliography Joel Davis, Mapping the Code: The Human Genome Project and the Choices of Modern Science, John Wiley & Sons, Inc., 1990. Thomas F. Lee, GENE FUTURE: The Promise and Perils of the New Biology, Plenum Press, New York, 1993. U.S. Congress, Office of Technology Assessment, New Developments in Biotechnology— Background Paper, Pubic Receptions of Biotechnology, OTA—BBP—BA—45, U.S. Government Printing Office, Washington, D.C., May 1987 quoted by George J. Annas and Sherman Elias, GENE MAPPING: Using law and Ethics as Guides, Oxford University Press, New York, 1992, page 144. Unknown author, Gene Therapy - An Overview, 1990, http://www.gene.com/AE/AB/IWT/Gene_Therapy_Overview.html

Diversity, equality and inclusion in a work setting Essay

Diversity means variety. The concept of diversity encompasses acceptance and respect. It means understanding that each individual is unique, and recognizing our individual differences. These can be along the dimensions of race, ethnicity, gender, sexual orientation, socio-economic status, age, physical abilities, religious beliefs, political beliefs, or other ideologies. It is the exploration of these differences in a safe, positive, and nurturing environment. It is about understanding each other and moving beyond simple tolerance to embracing and celebrating the rich dimensions of diversity contained within each individual. Diversity is a reality created by individuals and groups from a broad spectrum of demographic and philosophical differences. It is extremely important to support and protect diversity because by valuing individuals and groups free from prejudice, and by fostering a climate where equity and mutual respect are intrinsic. â€Å"Diversity† means more than just acknowledging and/or tolerating difference. Diversity is a set of conscious practices that involve: ï‚ §Understanding and appreciating interdependence of humanity, cultures, and the natural environment. ï‚ §Practicing mutual respect for qualities and experiences that are different from our own. ï‚ §Understanding that diversity includes not only ways of being but also ways of knowing; ï‚ §Recognizing that personal, cultural and institutionalized discrimination creates and sustains privileges for some while creating and sustaining disadvantages for others; ï‚ §Building alliances across differences so that we can work together to eradicate all forms of discrimination. Diversity includes, therefore, knowing how to relate to those qualities and conditions that are different from our own and outside the groups to which we belong, yet are present in other individuals and groups. These include but are not limited to age, ethnicity, class, gender, physical abilities/qualities, race, sexual orientation, as well as religious status, gender expression, educational background, geographical location, income, marital status, parental status, and work experiences. Finally, we acknowledge that categories of difference are not always fixed but also can be fluid, we respect individual rights to self-identification, and we recognize that no one culture is intrinsically superior to another. Health and social care settings reflect the diversity of the population at large. Residents in a care home for elderly people – men and women, possibly gay and lesbian – may range in age from 60 to well into their ninth decade. Each will have their own set of perso nal experiences and in locations with an immigrant community, may hail from a variety of different countries. And preferences, for example for food and music, will vary from one person to another, as will attitudes, for example to staff and fellow residents, beliefs, for example political ideas and religious faiths, health status and physical and intellectual ability. Apart from differences in age, sex and gender, physical characteristics, ability, experiences and personal attributes, people also differ in respect of their: Diet, for example different health conditions mean that some people have specific dietary needs, and vegetarians and vegans can’t take medication that is derived from animals. Religious faith, for example some religions have specific requirements with respect to diet and method of worship, others require the use of running water to maintain personal hygiene, the right hand for eating and the left for personal cleansing after using the toilet, and so on. Need for modesty and dignity, for example some people aren’t comfortable being touched or seen undressed by someone of the opposite sex or that they don’t know; and different people have different ideas about how to be addressed when being spoken to. Communication, for example different physical and mental health conditions require the use of different methods of communication; some people express their fear, pain and grief freely and openly whilst others are more reserved; and different people have different ideas about the extent of their personal space. Working with and getting to know a diverse range of people – service users, patients, their friends and family, colleagues and other professionals – enables health and social care workers to develop their knowledge and understanding of different ways of thinking and living and the reasons for different behaviours. As a consequence, tolerance of and respect for others develops, both of which are essential for meeting diverse – and individual – needs. And having their differences acknowledged and understood helps people to develop a sense of belonging. In addition, learning about different ways of thinking and living can be life-enriching. We become more open-minded to new experiences, opportunities and challenges, and are able to develop new relationships. As a result we grow as human beings and are able to achieve our full potential. Equality Equality is about treating people fairly, regardless of their differences, by ensuring that they have access to the same life opportunities as everyone else, ie that they have equal opportunities. Life opportunities include: Housing. Warmth and shelter are basic human needs. Education and employment. Just about everybody is capable of learning, and education not only enables us to find employment, it helps us to realize our full potential as human beings. Transport, without which we couldn’t get to work, to the shops, to see friends and family, to gp and hospital appointments, and so on. Health and social care, which all of us need at some point in our lives. Having enough money to buy a decent quality of life and not live in poverty. Being able to buy goods and services, in person, by telephone or online using cash, cheques, credit or debit cards or electronic transfer. Some people need extra help to access life opportunities. For example, having a physical or sensory disability can impact on gaining an education, a job, using public transport, getting to the doctors; and being elderly or mentally ill can affect an individual’s ability to maintain a decent standard of living, buy goods and services, speak up for themselves and have others listen to them. For this reason, equality is also about giving people help, providing them with appropriate services, so that they are not disadvantaged or treated less fairly than anyone else. People are disadvantaged for many reasons, but usually because they are different with respect to their: Appearance. Racial harassment and attacks are usually acted out on people whose appearance, for exam ple their skin colour and style of dress, is different from that of the perpetrator. Sex. Men are still more likely to be better paid than women and to reach the top of the career ladder, and some jobs are still perceived and advertised as being ’women’s’ or ‘men’s’ work. Sexual orientation. Gays and lesbians remain subject to physical and verbal abuse. Age. Older people often describe themselves as invisible, undervalued and a burden because of the way society treats them. Ability. A general lack of understanding about the needs of people with physical or mental disabilities results in them finding it very difficult to make the most of life’s opportunities. Imposing disadvantage on people can prevent them from entering into the everyday life of their community and of society. In other words they can become socially and financially excluded. Inclusion The term inclusion is seen as a universal human right and aims at embracing all people irrespective of race, gender, disability, medical or other need. It is about giving equal access and opportunities and getting rid of discrimination and intolerance. Inclusion nurtures a sense of wellbeing and of confidence in ones own identity and abilities. And it ensures that everyone can achieve their potent ial and take their rightful place in society. The potential effects of discrimination A prejudice is an attitude or way of thinking based on an unfounded, unreasonable pre-judgement of an individual, particular group of people or situation, rather than on a factual assessment. Prejudices can be positive or negative. If we are positively prejudiced towards someone, we think well of them. On the other hand, if we are negatively prejudiced against someone, we tolerate them less. In the main, negative prejudices develop against people who are different in some way. Discrimination happens when we act out our negative prejudices. Discriminatory behaviour results in unfair, unjust treatment. The people most likely to be discriminated against are those who are different in respect of their: Age. Age discrimination, or ageism, isn’t only targeted at elderly people – youngsters can also be on the receiving end of bullying, harassment and undeserved criticism. Sex. Men and women continue to be treated unfairly in certain walks of life, in particular in the workplace. Discrimination based on sex is known as sexism. Nationality, ethnic background, religion. Some people consider themselves superior to those from different backgrounds and faiths. Victimisation, bullying and harassment of people for such reasons is known as racism. Ability. Barriers that prevent disabled people from accessing the same opportunities as able-bodied people and the ignorant acting out of negative prejudices against physically or intellectually disabled people, for example through namecalling and damage of their property, is known as disablism. Size. Some of us are guilty of judging people by their size and treating them unfairly as a result. This behaviour is known as sizeism. Financial status. Discrimination against people on the grounds of their income, for example treating people living in poverty as inferior, is known as povertyism. There are two forms of discrimination, direct and indirect. Direct discrimination occurs when someone is intentionally treated unfairly, for example harassment on the basis of skin colour or religion. Indirect discrimination occurs when rules or guidelines meant to apply to everyone unintentionally affect one group of people more than others. For example, a company policy requiring everyone to work night shifts indirectly discriminates against single parents or people who care for elderly relatives, and menus that fail to offer a selection of food indirectly discriminates against people with specific dietary needs or preferences. Discrimination takes place in a variety of settings, for example within educational establishments, where learners may not be given support and encouragement if it’s assumed that their disability or advancing years affects their ability to learn; in the workplace, when people are persecuted on the basis of their skin colour or sexual preference. In housing, when landlords refuse to let their property to someone because of their refugee status or ethnic background; and in health and social care, when people are denied access to care on the basis of where they live – the postcode lottery. Inclusive work practice Inclusive practice is about the attitudes, approaches and strategies take n to ensure that people are not excluded or isolated. It means supporting diversity by accepting and welcoming people’s differences, and promoting equality by ensuring equal opportunities for all. Inclusive practice is best practise. Health and social care workers demonstrate inclusive practice by working in ways that recognise, respect, value and make the most of all aspects of diversity. Having a sound awareness of and responding sensitively to an individual’s diverse needs supports them in developing a sense of belonging, wellbeing and confidence in their identity and abilities. And it helps them to achieve their potential and take their rightful place in society. In addition, inclusive practice involves having an understanding of the disastrous impact that discrimination, inequality and social exclusion can have on an individual’s physical and mental health. Having such an understanding ensures appropriate, personalised care and support, thereby enabling an individual to develop selfrespect and maintain a valued role in society. Because people who fail to support diversity or promote equality are usually entirely unaware of their attitudes and the impact of their behaviour, inclusive practice in volves reflecting on and challenging ones own prejudices, behaviours and work practices. It also involves challenging those of colleagues and other service providers, with a view to adapting ways of thinking and working and to changing services to build on good practice and to better support diversity and promote equality. Discrimination is an injustice and has devastating effects. The UK has in place numerous pieces of legislation (laws), rules, regulations, guidance documents and statutory codes of practice, all of which are intended to promote diversity, ensure equality and end discrimination. In other words they are in place to promote everyone’s right to fair and equal treatment, regardless of their differences. Acts of Parliament and regulations include: ï€  Ã¯â‚¬  The Human Rights Act 1998. This covers many different types of discrimination, including some that are not covered by other discrimination laws. Rights under the Act can be used only against a public authority, for example, the police or a local council, and not a private company. However, court decisions on discrimination usually have to take into account what the Human Rights Act says. The Equality Act became law in October 2010. It replaces previous legislation (such as the Race Relations Act 1976 and the Disability Discri mination Act 1995) and ensures consistency in what you need to do to make your workplace a fair environment and to comply with the law. The Equality Act covers the same groups that were protected by existing equality legislation – age, disability, gender reassignment, race, religion or belief, sex, sexual orientation, marriage and civil partnership and pregnancy and maternity – but extends some protections to groups not previously covered, and also strengthens particular aspects of equality law. The Equality Act is a mixture of rights and responsibilities that have: Stayed the same – for example, direct discrimination still occurs when â€Å"someone is treated less favourably than another person because of a protected characteristic† Changed – for example, employees will now be able to complain of harassment even if it is not directed at them, if they can demonstrate that it creates an offensive environment for them Been extended – for example, associative discrimination (direct discrimination against someone because they associate with another person who possesses a protected characteristic) will cover age, disability, gender reassignment and sex as well as race, religion and belief and sexual orientation Been introduced for the first time – for example, the concept of discrimination arising from disability, which occurs if a disabled person is treated unfavourably because of something arising in consequence of their disabilit. Other pieces of legislation that protect the rights of people who use care services include: The NHS and Community Care Act 1980. This protects the rights of older and disabled people to receive care at home and in the community in ways that take account of their choices. The Children Act 2004. This protects children’s rights by requiring Local Authorities to be flexible in meeting their needs. Health and Social Care Act 2008. This Act established the Care Quality Commission (CQC), the remit of which is to protect and promote the right of people using health and social care services in England to quality care and to regulate its provision. CQC took over the roles of the Healthcare Commission, Commission for Social Care Inspection and the Mental Health Act Commission in March 2009. These pieces of legislation have helped us move forward on equality, but in 2009, women were still earning, on average, 23% less per hour than men; less able but better off children were overtaking m ore able, poorer children at school by the age of six; people with disabilities were still more than twice as likely to be out of work than able bodied people; and one in five older people was unsuccessful in getting quotations for motor insurance, travel insurance and car hire.

The Official Instructions to Start a Super PAC

So you want to start a super PAC. Maybe youre worried that your vote doesnt really matter. Maybe youre tired of other super PACs raising and spending unlimited amounts of cash from corporations and unions to sway elections and youre asking yourself If you cant beat em, why not join em? Not a problem. Thanks to the U.S. Supreme Court and Citizens United, anyone can start a super PAC. And the best part: It doesnt cost a dime. Never mind the Steven Colbert super PACs Super Fun Pack, which hilariously offers prospective activists, All you need is a burning desire for civic engagement and $99. Heres how to start a super PAC. For free. Just by signing your John Hancock on a couple pieces of paper. Step 1: Pick a Cause or Candidate First things first. Your super PAC doesnt have to target a politician, though it certainly can. Restore Our Future Inc., for example, is the pro-Mitt Romney super PAC that spent considerable sums of cash in Election 2012 going after the former Massachusetts governors Republican opponents, including Rick Santorum. Your super PAC can raise awareness about a particular cause or issue such as hydraulic fracking, abortion, or taxes. Yours can be a liberal super PAC or a conservative super PAC. Got a burning desire for civic engagement, as Colbert would put it, on a particular topic? Go for it. Step 2: Pick a Clever Name for Your Super PAC Youll want to name your super PAC something catchy. Something people will be able to easily remember when they break out their checkbooks. Already taken are Joe Six PAC, a super PAC that proclaims it is for the average Joe; the Sick and Tired of Washington super PAC, whose goals seem pretty obvious; and DogPAC, a super PAC representing Dogs Against Romney. Step 3: Other Essentials for Starting Your Own Super PAC All you need to create and run your official super PAC now are a bank account, a charming personality to raise all that money from corporations and unions, and a friend to serve as treasurer to keep track of your super PACs fundraising and spending. Pick someone who is trustworthy and responsible. Theyll need to file spending reports with the government. Step 4: File the Paperwork To officially launch your super PAC you will need to file whats called a Statement of Organization, or Form 1, with the Federal Election Commission. Check box 5(f) under Type of Committee. Also, write a short cover letter to the Federal Election Commission. Youll want to be sure you make it clear your new committee will be functioning as a super PAC. You can do that by including the following paragraph verbatim: This committee intends to make unlimited independent expenditures, and consistent with the U.S. Court of Appeals for the District of Columbia Circuit decision in SpeechNow v. FEC, it therefore intends to raise funds in unlimited amounts. This committee will not use those funds to make contributions, whether direct, in-kind, or via coordinated communications, to federal candidates or committees. Make sure to include your Statement of Organization your name, address, contact information, and the name of your super PAC and its treasurer. Mail your form to: Federal Election Commission 999 E. St., NW Washington, D.C. 20463 Step 5: What To Do With Your Super PAC As the proud new owner of a super PAC, you are permitted to raise unlimited amounts of money from people including your friends, neighbors, and families. But you can also solicit money from political action committees, corporations, and labor organizations. You can turn around and use all that money to produce and air TV commercials or take out a massive billboard along a busy highway to roundly criticizes a politician you dont like. Have fun and be creative! A Note of Caution: What You Cant Do With Your Super PAC This is pretty simple. You are not allowed to use all that money youve raised from corporations and unions to make direct contributions to candidates or their political action committees. You also cant take out TV ads or billboards in coordination with any of those candidates or their PACs. This is a fairly gray area, so play it safe and steer clear of planning your attacks with any candidate or elected official.